10 forms. 5 in the morning, 5 in the evening. The first dual-circadian magnesium formula — designed around the logic of your body.
Order Magnesium AM + PMMost magnesium supplements contain only one form — most often magnesium oxide, which has the lowest bioavailability (only ~4% absorption).
But magnesium is not just one mineral. It is a dynamic biological signal that behaves differently in the body in the morning than in the evening — because your body in the morning and in the evening is not biologically the same.
In the morning the body needs magnesium for cellular energy, mitochondria and nervous-system activation.
In the evening the body needs magnesium to calm the nervous system, support GABA receptors and regeneration.
One formula for both purposes cannot optimally cover either phase.
~4%
absorption of magnesium oxide
(the most common form)
30%+
absorption of organic forms
such as bisglycinate and citrate
Source: Walker et al. 2003, randomized crossover trial
EscapeMed Magnesium AM + PM is, to our knowledge, the first dual-circadian magnesium formula documented in the scientific literature. Five forms in the morning, five in the evening — each with precise biological logic.
Malate and succinate are deliberately excluded from the PM formula — mitochondrial stimulation is counterproductive during regeneration.
Taurate is deliberately excluded from the AM formula — GABAergic sedation is counterproductive in the activation phase.
The AM/PM magnesium architecture is, to our knowledge, the first dual multi-salt magnesium formulation documented in the scientific literature. → Read the full scientific rationale
About magnesium threonate (Magtein®)
Threonate is a category of its own — intended for cognitive support, taken separately. It is not a systemic magnesium and is not comparable to the AM/PM system. Anyone wanting cognitive support adds it alongside — not instead of — Magnesium AM + PM.
“One formula that combines all salts at the same time does not deliver biological signals — it delivers biological noise.”
Magnesium AM contains magnesium L-ascorbate — the only form of magnesium that simultaneously delivers active vitamin C (93–187 mg depending on dose).
Vitamin C is an obligatory cofactor for collagen synthesis without which synthesis does not proceed regardless of amino-acid quantity. Magnesium itself is involved in 300+ enzymatic processes, including processes of connective tissue.
So Magnesium AM is not just magnesium — it is also a morning support for collagen synthesis, which is activated precisely in the morning hours, when fibroblasts are naturally most active.
Vitamin C in Magnesium AM
1 capsule in the morning
93.5 mg
117% of the daily reference value
2 capsules in the morning
187 mg
234% of the daily reference value
EU-approved health claim: vitamin C contributes to normal collagen formation*
Despite enough sleep you feel tired in the morning. You have a pronounced afternoon energy slump. Magnesium malate and succinate enter the mitochondrial energy cycle — magnesium contributes to the reduction of tiredness and fatigue.*
The decline in estrogen reduces magnesium reabsorption in the kidneys. A multi-salt AM/PM formula maximizes absorption through several transport mechanisms simultaneously.
Magnesium is essential for neuromuscular function and for supporting normal muscle function.* The PM formula with lactate supports nocturnal replenishment of glycogen stores.
Magnesium taurate has a particular affinity for brain tissue. Vitamin B6 contributes to normal psychological function and to normal function of the nervous system.*
Magnesium taurate activates extrasynaptic GABA-A receptors in the thalamus — this is the biological mechanism of the ingredient, not a health claim. The PM formula is an evening signal for the body, not a sleeping pill and not a remedy for insomnia.
The AM formula with vitamin C and bisglycinate (a precursor to glutathione) supports the conditions for collagen synthesis from within — during morning hours, when fibroblasts are most active.
Caffeine directly increases magnesium excretion through urine. Chronic stress depletes magnesium via the cortisol axis. These are two of the most common reasons for subclinical deficiency in otherwise healthy and active people.
Magnesium is not just for solving problems. It is the foundation for the normal function of 300+ enzymatic processes. Those who feel good take it preventively — so the body maintains optimal levels and does not start to run low.
An optimal magnesium level is one of the key markers of biological age. Don't wait for symptoms of deficiency — magnesium works as a long-term foundation, not a quick fix.
Each formula is built at 125 mg of elemental magnesium per capsule — for two dosing levels.
Starting dose
1+1
1 capsule AM + 1 capsule PM
250 mg of elemental magnesium/day
Standard dose
2+2
2 capsules AM + 2 capsules PM
500 mg of elemental magnesium/day
Each pack contains 60 capsules — enough for 30 days at the standard dose.
20–30% of Europeans do not get enough magnesium from their diet. The body sends clear signals — do you recognize them?
Energy and concentration
Muscles and nervous system
Important: Magnesium deficiency is often subclinical — a standard blood test (serum magnesium) reflects only 1% of total body stores and often fails to detect a deficit. The body compensates by releasing magnesium from bones and tissues. The presence of any of the signs listed above is reason to consider supplementation. Food supplements are not medicine.
Two formulas. Ten forms. One complete circadian cycle of magnesium for your body.